act(a(CHEBI:acetylcholine)) increases act(p(HGNC:CHRM1))

PubMed:24511233

Two novel M4-selective compounds, VU10010 and LY2033298, represented a breakthrough when they were described in 2008.84,85 VU10010 is a potent M4-selective PAM that increases affinity/efficacy of ACh to promote M4 mAChR activation.

Related Edges 1

• a(HBP:VU10010) increases act(a(CHEBI:acetylcholine))

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