act(complex(GO:"protein phosphatase type 2A complex")) increases act(p(HGNC:GSK3B))

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PubMed:24653673

Specific PP2A inhibition has been proven to lead to in vivo deregulation of many major brain Ser/Thr kinases implicated in AD, including GSK3β (Wang et al., 2010; Louis et al., 2011), cdk5 (Louis et al., 2011; Kimura et al., 2013), extracellular signal- regulated kinase (ERK) and JNK (Kins et al., 2003).

Related Edges 3

• act(complex(GO:"protein phosphatase type 2A complex")) increases act(p(HGNC:CDK5))
• act(complex(GO:"protein phosphatase type 2A complex")) increases act(p(FPLX:ERK))
• act(complex(GO:"protein phosphatase type 2A complex")) increases act(p(FPLX:JNK))

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