p(HGNC:HTT, var("?")) increases a(HBP:"huntingtin aggregates")

PubMed:14556719

However, a contribution to the pathogenesis by loss of function of Huntingtin encoded from the wild-type allele has not been excluded in HD (Cattaneo et al., 2001), since the mutant protein not only aggregates itself but can also promote aggregation of the wild-type protein (Busch et al.,2003).

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