p(MGI:Nlrp3) decreases bp(GO:cognition)

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PubMed:24561250

In support, knockout of NLRP3 and caspase-1 have been shown to suppress amyloidogenesis and neuropathology, and improve cognition in AD transgenic mice (Heneka et al., 2013)

Related Edges 5

• p(MGI:Casp1) increases bp(GO:"amyloid-beta formation")
• p(MGI:Casp1) increases a(MESH:Neuropathology)
• p(MGI:Casp1) decreases bp(GO:cognition)
• p(MGI:Nlrp3) increases bp(GO:"amyloid-beta formation")
• p(MGI:Nlrp3) increases a(MESH:Neuropathology)

Confidence

High

MeSH

Alzheimer Disease

NeuroMMSigDB

Caspase subgraph

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