p(HGNC:CFTR, var("p.Phe508del")) increases deg(p(HGNC:CFTR))

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PubMed:14556719

This case may be analogous to the loss of function observed during the rapid degradation of mutated ΔF508 Cystic Fibrosis Transmembrane conductance Regulator (CFTR), which is also an active protein, and that the rapid degradation of which contributes to the pathogenesis of cystic fibrosis (CF) in patients carrying the mutation

Related Edges 1

• p(HGNC:CFTR, var("p.Phe508del")) increases path(MESH:"Cystic Fibrosis")

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