p(HGNC:TICAM1) increases act(p(HGNC:IRF3))

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PubMed:24904418

The MyD88-dependent pathway leads to the activation of mitogen-activated protein kinases (MAPKs) and NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) transcription factors inducing the expression of inflammatory cytokines such as TNF, IL-6, IL-1β, and KC (Takeuchi and Akira, 2010)

Related Edges 2

• act(p(HGNC:IRF3)) increases p(HGNC:IFNA1)
• act(p(HGNC:IRF3)) increases p(HGNC:NFKB1)

Cell Ontology (CL)

leukocyte

MeSH

Liver

MeSH

Malaria

Text Location

Review

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