a(CHEBI:"amyloid-beta") regulates act(p(FPLX:CHRN))

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PubMed:25514383

Modulation of nAChRs by Abeta was also found in ex vivo studies: Pettit and colleagues (2001) used rat hippocampal slices to show that Abeta1-42 incubation is able to reduce postsynaptic currents and open probability of both alpha7 and non-alpha7 nAChRs subtypes, demonstrating an interaction between Abeta and other nAChR subunits

Related Edges 1

• a(CHEBI:"amyloid-beta polypeptide 42") decreases bp(MESH:"Synaptic Potentials")

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