p(HGNC:MAPT) increases path(MESH:"Nerve Degeneration")

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PubMed:24027553

Given that in animal models of AD reducing tau levels attenuates neuronal dysfunction (7, 8), and in humans the extent of tau pathology correlates with cognitive decline (9), there is a growing interest in defining the degradative pathways that remove tau from the cell.

Related Edges 2

• path(MESH:"Cognitive Dysfunction") positiveCorrelation path(MESH:Tauopathies)
• path(MESH:Tauopathies) positiveCorrelation path(MESH:"Cognitive Dysfunction")

MeSH

Alzheimer Disease

Text Location

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