a(CHEBI:"amyloid-beta") association path(MESH:"Alzheimer Disease")

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PubMed:14556719

Taken together, several lines of evidence point to a reduced UPS function in AD and suggest that both Abeta and tau are important players in the game.

Related Edges 5

• bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process") negativeCorrelation path(MESH:"Alzheimer Disease")
• p(HGNC:MAPT) association path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") negativeCorrelation bp(GO:"proteasome-mediated ubiquitin-dependent protein catabolic process")
• path(MESH:"Alzheimer Disease") association a(CHEBI:"amyloid-beta")
• path(MESH:"Alzheimer Disease") association p(HGNC:MAPT)

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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