a(HBP:HBP00067) negativeCorrelation path(MESH:"Alzheimer Disease")

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PubMed:21214928

A dramatically reduced ADAM10 protein level in the platelets of sporadic AD patients was also found to correlate with the significantly decreased sAPPalpha levels found in their platlets and cerebrospinal fluid [55] and the reduced alpha-secretase activity in the temporal cortex homogenates of AD patients [56]

Related Edges 5

• p(HGNC:ADAM10) negativeCorrelation path(MESH:"Alzheimer Disease")
• act(p(HGNC:ADAM10)) negativeCorrelation path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") negativeCorrelation p(HGNC:ADAM10)
• path(MESH:"Alzheimer Disease") negativeCorrelation act(p(HGNC:ADAM10))
• path(MESH:"Alzheimer Disease") negativeCorrelation a(HBP:HBP00067)

Confidence

Medium

MeSH

Blood Platelets

MeSH

Cerebrospinal Fluid

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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