a(CHEBI:tacrine) increases act(p(HGNC:ACHE))

View Subject View Object

PubMed:11230871

It is likely that the therapeutic benefit of cholinesterase inhibitors occurs at least in part through activation of the nAChRs, by the direct action of increased levels and/or through a direct activation of the allosteric site on the nAChR (Maelicke et al 1995, 2000)

Related Edges 3

• a(CHEBI:donepezil) increases act(p(HGNC:ACHE))
• a(CHEBI:galanthamine) increases act(p(HGNC:ACHE))
• a(CHEBI:rivastigmine) increases act(p(HGNC:ACHE))

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---