path(MESH:"Neurodegenerative Diseases") association bp(GO:"regulation of endosome size")

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PubMed:22908190

Neuronal endosome enlargement, which is not characteristically observed in other major neurodegenerative diseases, develops in pyramidal neurons of the neocortex at a stage when plaques and tangles are restricted only to the hippocampus (Braak stage 2) and not in brains of similarly aged individuals free of AD-like hippocampal pathology (Cataldo et al. 1997, 2000).

Related Edges 3

• a(HBP:"Braak_Stage II") association bp(GO:"regulation of endosome size")
• bp(GO:"regulation of endosome size") association path(MESH:"Neurodegenerative Diseases")
• bp(GO:"regulation of endosome size") association a(HBP:"Braak_Stage II")

MeSH

Neocortex

MeSH

Neurons

MeSH

Pyramidal Cells

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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