a(CHEBI:heme) increases p(HGNC:HMOX1)

View Subject View Object

PubMed:26675351

Consistently, CD11b cells (granulocytes and monocytes) and iron-rich cells (macrophages) isolated from heme-treated Hx-null mice show a higher heme content and increased mRNA and protein expression of HO-1, Lferritin, and Fpn (Figure 1B-G) and elevated mRNA levels of the proinflammatory cytokine IL-6 ( Figure 1H).

Related Edges 4

• a(CHEBI:heme) increases r(HGNC:HMOX1)
• a(CHEBI:heme) increases p(HGNC:FTL)
• a(CHEBI:heme) increases p(PFAM:FPN1)
• a(CHEBI:heme) increases r(HGNC:IL6)

MeSH

Liver

MeSH

Anemia, Sickle Cell

Text Location

Results

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---