p(HGNC:CNTF) increases a(MESH:"Transcription Factor AP-1")

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PubMed:28745240

NF-κB positively regulates the transcription of interleukin 6 (IL6) family of cytokines such as IL6, leukemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) [184], which in-turn induce the differentiation of NSC into astrocytes by activating transcription factors STAT3, AP-1, and NF-κB itself

Related Edges 17

• a(MESH:"Transcription Factor AP-1") increases bp(GO:"astrocyte development")
• complex(GO:"NF-kappaB complex") increases p(HGNC:IL6)
• act(complex(GO:"NF-kappaB complex")) increases bp(GO:"astrocyte development")
• complex(GO:"NF-kappaB complex") increases p(HGNC:LIF)
• complex(GO:"NF-kappaB complex") increases p(HGNC:CNTF)
• p(HGNC:CNTF) increases bp(GO:"astrocyte development")
• p(HGNC:CNTF) increases p(HGNC:STAT3)
• p(HGNC:CNTF) increases act(complex(GO:"NF-kappaB complex"))
• p(HGNC:IL6) increases bp(GO:"astrocyte development")
• p(HGNC:IL6) increases p(HGNC:STAT3)
• p(HGNC:IL6) increases a(MESH:"Transcription Factor AP-1")
• p(HGNC:IL6) increases act(complex(GO:"NF-kappaB complex"))
• p(HGNC:LIF) increases bp(GO:"astrocyte development")
• p(HGNC:LIF) increases p(HGNC:STAT3)
• p(HGNC:LIF) increases a(MESH:"Transcription Factor AP-1")
• p(HGNC:LIF) increases act(complex(GO:"NF-kappaB complex"))
• p(HGNC:STAT3) increases bp(GO:"astrocyte development")

MeSH

Alzheimer Disease

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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