a(CHEBI:chlorohydroquinone) decreases bp(GO:macroautophagy)

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PubMed:30116051

Indeed, clioquinol countered disruption of autophagy by chloroquine in retinal cells, reduced Aβ42 accumulation in CHO cells expressing APP and mutant presenilin 1 and diminished amyloid misfolding and aggregation in Tg2576 AD mice 196,197 .

Related Edges 2

• a(CHEBI:"5-chloro-7-iodoquinolin-8-ol") increases bp(GO:macroautophagy)
• a(CHEBI:"5-chloro-7-iodoquinolin-8-ol") decreases a(CHEBI:"amyloid-beta polypeptide 42")

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