bp(GO:"response to endoplasmic reticulum stress")
to bp(GO:"cell death")
The three sensors of ER proteotoxic stress facilitate contra- dictory responses since they either promote cell survival by decreasing the misfolded protein and/or oxidative load, or, if UPR fails, they promote the activation of apoptotic pathways that eventually result in cell death [57].
bp(GO:"response to endoplasmic reticulum stress") decreases bp(GO:"cell death")
3837b50330
bp(GO:"response to endoplasmic reticulum stress") increases bp(GO:"cell death")
1c7b89829b
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.