PubMed 29626319

Among MMPs, MMP-2, -3 and -9, stimulated by Aβ, play important roles in degrading Aβ (Wang et al. 2014)

BEL
a(CHEBI:"amyloid-beta") increases act(p(HGNC:MMP9))
Hash
27e9de36fb
Networks
BEL
act(p(HGNC:MMP9)) increases deg(a(CHEBI:"amyloid-beta"))
Hash
be0ef8d254
Networks

PubMed 29626319

Exercise training can increase extracellular Aβ clearance in the brains of Tg2576 mice in a dose-dependent manner through up-regulating NEP, IDE, MMP9, LRP1, and HSP70 (Moore et al. 2016)

BEL
p(HGNC:MMP9) increases deg(a(CHEBI:"amyloid-beta"))
Hash
b8debd9d8d
Networks

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.