1. Catalog
  2. Citations
  3. PubMed:23134599

PubMed: 23134599

Title
Early postnatal lead exposure induces tau phosphorylation in the brain of young rats.
Journal
Acta biologica Hungarica
Volume
63
Issue
None
Pages
411-25
Date
2012-12-01
Authors
Al-Khaledi G | Attur S | Khan I | Khan KM | Rahman A

Evidence e737587a8d
JSON

PP2A expression decreased, whereas, PP1 and PP5 expression increased in lead-exposed rats. These results demonstrate that early postnatal exposure to lead decrease PP2A expression and induce tau hyperphosphorylation at several serine and threonine residues.

a(CHEBI:"lead diacetate") increases p(RGD:Ppp1ca) View Subject | View Object

Appears in Networks:

a(CHEBI:"lead diacetate") increases p(RGD:Ppp5c) View Subject | View Object

Appears in Networks:

a(CHEBI:"lead diacetate") decreases p(RGD:Ppp2ca) View Subject | View Object

Appears in Networks:

p(MGI:Mapt, pmod(HBP:hyperphosphorylation)) negativeCorrelation p(RGD:Ppp2ca) View Subject | View Object

Appears in Networks:

p(RGD:Ppp2ca) negativeCorrelation p(MGI:Mapt, pmod(HBP:hyperphosphorylation)) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.