p(MGI:Mapt, pmod(HBP:hyperphosphorylation)) negativeCorrelation p(RGD:Ppp2ca)

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PubMed:23134599

PP2A expression decreased, whereas, PP1 and PP5 expression increased in lead-exposed rats. These results demonstrate that early postnatal exposure to lead decrease PP2A expression and induce tau hyperphosphorylation at several serine and threonine residues.

Related Edges 4

• a(CHEBI:"lead diacetate") increases p(RGD:Ppp1ca)
• a(CHEBI:"lead diacetate") increases p(RGD:Ppp5c)
• a(CHEBI:"lead diacetate") decreases p(RGD:Ppp2ca)
• p(RGD:Ppp2ca) negativeCorrelation p(MGI:Mapt, pmod(HBP:hyperphosphorylation))

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