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PubMed: 19765634

Title
Ubc9 gene polymorphisms and late-onset Alzheimer's disease in the Korean population: a genetic association study.
Journal
Neuroscience letters
Volume
465
Issue
None
Pages
272-5
Date
2009-11-20
Authors
Ahn K | Jo SA | Kim DK | Koh YH | Park MH | Song JH

Evidence caa2b1b429
JSON

The genotype distribution of a polymorphism in intron 7 (rs761059) differed between AD cases and controls, with an adjusted odds ratio (OR) of 1.45 (p=0.046, 95% CI: 1.01-2.08). One haplotype (ht2 CAGAG) was found in 14.0% of the AD patients and in 11.1% of the controls (p=0.04, OR=1.43. 95% CI; 1.01-2.01). Stratification by the ApoE gave no significant difference between the groups but when stratified by gender, two SNPs (rs8052688, rs8063) were significantly associated with the risk of MCI among women.

g(DBSNP:rs761059) positiveCorrelation path(MESH:"Alzheimer Disease") View Subject | View Object

Appears in Networks:

g(DBSNP:rs8052688) positiveCorrelation path(MESH:"Cognitive Dysfunction") View Subject | View Object

Appears in Networks:
Annotations
Gender
Female

g(DBSNP:rs8063) positiveCorrelation path(MESH:"Cognitive Dysfunction") View Subject | View Object

Appears in Networks:
Annotations
Gender
Female

path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs761059) View Subject | View Object

Appears in Networks:

path(MESH:"Cognitive Dysfunction") positiveCorrelation g(DBSNP:rs8052688) View Subject | View Object

Appears in Networks:
Annotations
Gender
Female

path(MESH:"Cognitive Dysfunction") positiveCorrelation g(DBSNP:rs8063) View Subject | View Object

Appears in Networks:
Annotations
Gender
Female

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