path(MESH:"Cognitive Dysfunction") positiveCorrelation g(DBSNP:rs8052688)

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PubMed:19765634

The genotype distribution of a polymorphism in intron 7 (rs761059) differed between AD cases and controls, with an adjusted odds ratio (OR) of 1.45 (p=0.046, 95% CI: 1.01-2.08). One haplotype (ht2 CAGAG) was found in 14.0% of the AD patients and in 11.1% of the controls (p=0.04, OR=1.43. 95% CI; 1.01-2.01). Stratification by the ApoE gave no significant difference between the groups but when stratified by gender, two SNPs (rs8052688, rs8063) were significantly associated with the risk of MCI among women.

Related Edges 5

• g(DBSNP:rs761059) positiveCorrelation path(MESH:"Alzheimer Disease")
• g(DBSNP:rs8052688) positiveCorrelation path(MESH:"Cognitive Dysfunction")
• g(DBSNP:rs8063) positiveCorrelation path(MESH:"Cognitive Dysfunction")
• path(MESH:"Alzheimer Disease") positiveCorrelation g(DBSNP:rs761059)
• path(MESH:"Cognitive Dysfunction") positiveCorrelation g(DBSNP:rs8063)

Gender

Female

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