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PubMed: 14642273

Title
Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.
Journal
Neuron
Volume
40
Issue
None
Pages
471-83
Date
2003-10-30
Authors
Cruz JC | Goldman JA | Shih H | Tsai LH | Tseng HC

Evidence a3158bc6ff
JSON

Tau peptides containing phosphorylated S202, T205, and T396 were found only in Tg mice, supporting our results using AT8 and PHF1 antibodies

p(HBP:"CDK5R1 p25") directlyIncreases act(p(MGI:Cdk5), ma(kin)) View Subject | View Object

Appears in Networks:

p(HBP:"CDK5R1 p25") increases p(HBP:"Tau aggregates") View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 175)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 176)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 178)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 195)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 198)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(HBP:"Tau epitope, AT8") View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 217)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 220)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 235)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 239)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 396)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Ser, 400)) View Subject | View Object

Appears in Networks:

act(p(MGI:Cdk5), ma(kin)) directlyIncreases p(MGI:Mapt, pmod(Ph, Thr, 403)) View Subject | View Object

Appears in Networks:

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