path(MESH:"Muscle Rigidity") positiveCorrelation path(MESH:"Parkinson Disease")

PubMed:19126755

Parkinson’s disease (PD) is characterized by selective damage to dopaminergic nigrostriatal neurons and is clinically revealed by motor deficits, including rigidity, tremor, and bradykinesia. Dopamine replacement therapy (usually with L-dopa) is the most common treatment, although this drug loses efficacy over time.

Related Edges 6

• a(CHEBI:dopamine) decreases path(MESH:"Parkinson Disease")
• path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:Tremor)
• path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:Hypokinesia)
• path(MESH:"Parkinson Disease") positiveCorrelation path(MESH:"Muscle Rigidity")
• path(MESH:Hypokinesia) positiveCorrelation path(MESH:"Parkinson Disease")
• path(MESH:Tremor) positiveCorrelation path(MESH:"Parkinson Disease")

MeSH

Dopaminergic Neurons

Text Location

Review

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