p(HGNC:HS6ST1) increases a(HBP:"6-O-sulfated heparin")

PubMed:29686391

Previous reports had indicated that internalization of tau could be regulated by HSPGs16, but our identification of HS6ST1, an enzyme that is responsible for 6-O-sulfation of HSPGs, supports a hypothesis that specific motifs on HSPGs might be important for tau uptake

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.