a(CHEBI:"methylene blue") increases bp(GO:autophagy)

View Subject View Object

PubMed:30116051

Other compounds that act through AMPK acti- vation include the antiaggregant methylene blue (Supplementary Box 1), which elevated levels of beclin  1, p62 and LC3, induced autophagy and suppressed tau in organotypic neuronal cultures and a mouse model of FTD 101,102 .

Related Edges 5

• a(CHEBI:"methylene blue") increases act(p(FPLX:AMPK))
• a(CHEBI:"methylene blue") increases p(HGNC:BECN1)
• a(CHEBI:"methylene blue") increases p(HGNC:MAP1LC3A)
• a(CHEBI:"methylene blue") increases p(HGNC:DCTN4)
• a(CHEBI:"methylene blue") decreases act(p(HGNC:MAPT))

MeSH

Dopaminergic Neurons

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---