p(HGNC:PSMD14) decreases complex(a(MESH:Proteins), a(MESH:Ubiquitin))

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PubMed:24457024

This observation suggests that chain binding and cleavage from the protein substrate are tightly coordinated by the proteasome, and may help to prevent situations such as premature chain cleavage by Rpn11, which could result in the release of the substrate before it becomes actively engaged to the proteasome.

Related Edges 1

• complex(GO:"proteasome complex") regulates complex(a(MESH:Proteins), a(MESH:Ubiquitin))

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