p(HGNC:MAPT, frag("292_319")) increases bp(GO:"actin filament bundle assembly")

PubMed:29215007

Tau(292–319) comprises the residues of repeat R2 and R3, which experience strong signal attenuation upon addition of F-actin to full-length Tau (Fig. 1e, f). In agreement with the ability of Tau(292–319) to bind to F-actin, the peptide promotes bundling of actin filaments (Supplementary Fig. 5c)

Confidence

High

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