p(MGI:Prdx2, pmod(Ox)) positiveCorrelation a(HM:"stored erythrocytes")

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PubMed:25264713

Figure 1B presents these data and shows that (i) basal (time 0) Prx-2 oxidation was higher at day 35 relative to day 14 and 28 ( p < 0.05 by one-way analysis of variance (ANOVA) with Tukey post hoc test); (ii) H2O2 significantly increased Prx-2 oxidation, which was maximal at the first time point (5 min) measured; (iii) the magnitude of the maximal level of Prx-2 oxidation increased with RBC storage age ( p < 0.05 by one-way ANOVA with Tukey post hoc test for day 7 vs. 35 for 5 min data); and (iv) dimeric Prx-2 was slowly reduced back to the monomer over 60 min; however, this was not observed with day 35 RBC, where Prx- 2 remained > 75% oxidized.

Related Edges 3

• a(CHEBI:"hydrogen peroxide") positiveCorrelation p(MGI:Prdx2, pmod(Ox))
• a(HM:"stored erythrocytes") positiveCorrelation p(MGI:Prdx2, pmod(Ox))
• p(MGI:Prdx2, pmod(Ox)) positiveCorrelation a(CHEBI:"hydrogen peroxide")

Cell Ontology (CL)

erythrocyte

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