p(MGI:Mapt, var("p.Pro301Leu")) increases p(MGI:Cdkn2a)
Moreover, Cdkn2a was expressed at levels 2.7- and 2.6-fold higher in tauNFT than CTL and tauWT, respectively (P = 0.0303 and P = 0.0352, respectively; Figure 1g); this effect was replicated in an independent mouse cohort (P = 0.0016, Figure S1g)
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.