bp(HM:"Monocyte-platelet aggregation") positiveCorrelation path(HP:"Arterial occlusion")

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PubMed:29929138

Although aggregation has not been investigated in PNH, we clearly show here that in primary Cys89Tyr CD59 mutation there is a significant increase in coaggregation with high numbers of activated platelets adhering to a single monocyte, and granulocytes to monocytes, that may lead to nonendothelial-bound arterial occlusion, among other effects [36].

Related Edges 3

• bp(HM:"Monocyte-platelet aggregation") positiveCorrelation p(HGNC:CD59, var("p.Cys89Tyr"))
• p(HGNC:CD59, var("p.Cys89Tyr")) positiveCorrelation bp(HM:"Monocyte-platelet aggregation")
• path(HP:"Arterial occlusion") positiveCorrelation bp(HM:"Monocyte-platelet aggregation")

Cell Ontology (CL)

erythrocyte

MeSH

Endothelium

MeSH

Hemoglobinuria, Paroxysmal

Text Location

Discussion

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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