a(CHEBI:"phosphatidyl-L-serine") increases path(MESH:Thrombosis)

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PubMed:25307023

The abnormal phospholipid membrane asymmetry present in the RBCs of b-thalassaemia and SCD patients, with resultant phosphatidylserine exposure, appears to play a significant role in the aetiology of the observed hypercoagulable state and in the link between haemolysis and thrombosis (Ataga et al, 2007).

Related Edges 3

• a(CHEBI:"phosphatidyl-L-serine") positiveCorrelation path(HP:Hypercoagulability)
• a(CHEBI:"phosphatidyl-L-serine") increases path(MESH:Hemolysis)
• path(HP:Hypercoagulability) positiveCorrelation a(CHEBI:"phosphatidyl-L-serine")

Cell Ontology (CL)

erythrocyte

MeSH

Plasma

MeSH

Urine

MeSH

Anemia, Sickle Cell

MeSH

beta-Thalassemia

Text Location

Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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