bp(GO:"CD4-positive, alpha-beta T cell activation") decreases act(complex(GO:"NLRP3 inflammasome complex"))

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PubMed:23702978

Thus, it is not surprising that effector and memory CD4+ T cells have the capacity to inhibit the activation of the NLRP1 and NLRP3 inflammasomes in a contact-dependent manner, possibly via TNFR superfamily molecules such as CD40 ligand (CD40L)70.

Related Edges 1

• bp(GO:"CD4-positive, alpha-beta T cell activation") decreases act(complex(GO:"NLRP1 inflammasome complex"))

Confidence

High

NeuroMMSigDB

Caspase subgraph

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