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bp(GO:"CD4-positive, alpha-beta T cell activation")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
CD4-positive, alpha-beta T cell activation
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 1

Activation and regulation of the inflammasomes v1.0.0

In-Edges 0

Out-Edges 2

bp(GO:"CD4-positive, alpha-beta T cell activation") decreases act(complex(GO:"NLRP1 inflammasome complex")) View Subject | View Object

Thus, it is not surprising that effector and memory CD4+ T cells have the capacity to inhibit the activation of the NLRP1 and NLRP3 inflammasomes in a contact-dependent manner, possibly via TNFR superfamily molecules such as CD40 ligand (CD40L)70. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Caspase subgraph

bp(GO:"CD4-positive, alpha-beta T cell activation") decreases act(complex(GO:"NLRP3 inflammasome complex")) View Subject | View Object

Thus, it is not surprising that effector and memory CD4+ T cells have the capacity to inhibit the activation of the NLRP1 and NLRP3 inflammasomes in a contact-dependent manner, possibly via TNFR superfamily molecules such as CD40 ligand (CD40L)70. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Caspase subgraph

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.