a(MESH:"Receptors, N-Methyl-D-Aspartate") increases act(p(HGNC:RAC1))

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PubMed:27796283

CaMKs functionally link NMDA (N-methyl-d-aspartate) receptors to Rac1 activation via the phosphorylation of specific guanine nucleotide exchange factors (GEFs) such as Kalirin-7, TIAM1 and β-PIX

Related Edges 8

• a(MESH:"Receptors, N-Methyl-D-Aspartate") increases p(HGNC:TIAM1, pmod(Ph))
• p(HBP:"Kalirin 7", pmod(Ph, Thr, 95)) increases act(p(HBP:"Kalirin 7"))
• act(p(HBP:"Kalirin 7")) increases act(p(HGNC:RAC1))
• act(p(HGNC:ARHGEF7)) increases act(p(HGNC:RAC1))
• p(HGNC:ARHGEF7, pmod(Ph, Ser, 516)) increases act(p(HGNC:ARHGEF7))
• p(HGNC:CAMK1) increases p(HGNC:ARHGEF7, pmod(Ph, Ser, 516))
• p(HGNC:CAMK2B) increases p(HBP:"Kalirin 7", pmod(Ph, Thr, 95))
• p(HGNC:TIAM1, pmod(Ph)) increases act(p(HGNC:RAC1))

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