a(CHEBI:"amyloid-beta polypeptide 42") decreases bp(MESH:"Synaptic Potentials")

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PubMed:25514383

They demonstrated that Abeta1-42 drives a reversible inhibition of nAChR-mediated currents in hippocampal GABAergic neurons recorded from rat slices. In these experimental conditions the most effective Abeta1-42 concentration was 500 nM, but inhibition was found also at the lower concentration of 100 nM

Related Edges 2

• a(CHEBI:"amyloid-beta polypeptide 42") decreases act(p(FPLX:CHRN))
• act(p(FPLX:CHRN)) increases bp(MESH:"Synaptic Potentials")

Cell Ontology (CL)

GABAergic neuron

MeSH

Hippocampus

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