p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) negativeCorrelation p(MGI:Gfap)

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PubMed:27671637

Surprisingly, expression of neuronal activity marker cFos, astrocytic activity marker Gfap, and oxidative stress marker Hmox1 were reduced in the proaggregant Tau transgenic slices, whereas antiaggregant Tau transgenic slices were not different from littermate controls (Fig. 4A)

Related Edges 14

• act(a(MESH:Neurons)) negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
• bp(GO:"astrocyte activation") negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
• bp(GO:"response to oxidative stress") negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
• p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) negativeCorrelation act(a(MESH:Neurons))
• p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) negativeCorrelation p(MGI:Fos)
• p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) negativeCorrelation bp(GO:"astrocyte activation")
• p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) negativeCorrelation bp(GO:"response to oxidative stress")
• p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) negativeCorrelation p(MGI:Hmox1)
• p(MGI:Fos) negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
• p(MGI:Fos) biomarkerFor act(a(MESH:Neurons))
• p(MGI:Gfap) negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
• p(MGI:Gfap) biomarkerFor bp(GO:"astrocyte activation")
• p(MGI:Hmox1) negativeCorrelation p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del"))
• p(MGI:Hmox1) biomarkerFor bp(GO:"response to oxidative stress")

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