bp(GO:"phosphatidylinositol 3-kinase signaling") regulates r(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")

PubMed:19126755

In cell lines, this interaction of trans-activating components is also under the regulation of the Ras-dependent MAPK and pathways related to phosphoinositide-3-kinase (PI3K) and MEK activation whose response to trophic factors such as nerve growth factor (NGF) contributes to regulating transcript initiation.

Related Edges 2

• bp(GO:"MAPK cascade") regulates r(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits")
• act(p(HGNC:NGF)) increases bp(GO:"MAPK cascade")

Text Location

Review

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.