Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

Provenance

PubMed:28314763

The mechanism postulated for the beneficial effects 398 of hemopexin in mouse models of chronic hemolysis involves inhibition of heme399 dependent activation of TLR4 signaling and a combination of reduced endothelial 400 formation of reactive oxygen species and restored endothelial NOS-activity.

Annotations 4

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.