a(HBP:"Tau oligomers") decreases a(GO:synapse)

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PubMed:28420982

These tau oligomers potentiate neuronal damage, leading to neurodegeneration and traumatic brain injury (Hawkins et al., 2013; Gerson et al., 2014a, 2016; Sengupta et al., 2015). Moreover, they have been implicated in synaptic loss as shown in studies of wild-type human tau transgenic mice (Spires et al., 2006; Berger et al., 2007; Clavaguera et al., 2013)

Related Edges 2

• a(HBP:"Tau oligomers") increases bp(HP:Neurodegeneration)
• a(HBP:"Tau oligomers") increases path(MESH:"Brain Injuries, Traumatic")

Confidence

High

MeSH

Cerebral Cortex

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