act(complex(GO:"proteasome complex")) negativeCorrelation bp(GO:aging)

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PubMed:22908190

Beyond an age-related reduction (Keller et al. 2002), proteasome activities decrease in AD in a brain region–specific manner, particularly in hippocampus, parahippocampal gyrus, superior and middle temporal gyri, and the inferior parietal lobule (Keller et al. 2000), areas that are especially critical for long-term memory formation.

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• bp(GO:aging) negativeCorrelation act(complex(GO:"proteasome complex"))

MeSH

Parahippocampal Gyrus

MeSH

Parietal Lobe

MeSH

Temporal Lobe

MeSH

Alzheimer Disease

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