path(HBP:"Argyrophilic Grain Disease") positiveCorrelation p(HBP:"4R tau")

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PubMed:26751493

On the other side, sarkosyl extracts from the filaments of PSP [129], corticobasal degeneration (CBD; [130]), argyrophilic grain disease (AgD; [131]), and some cases of FTDP-17, contain tau protein that separates as doublets of 64 and 69 kDa and are predominantly composed of tau isoforms with 4R (class II tauopathies), whereas sarkosyl extracts from filaments of Pick’s disease are characterized by the presence of pathological tau doublets of 60 and 64 kDa and contain mainly 3R tau isoforms (class III tauopathy).

Related Edges 7

• p(HBP:"3R tau") positiveCorrelation path(MESH:"Niemann-Pick Diseases")
• p(HBP:"4R tau") positiveCorrelation path(HBP:"Corticobasal Degeneration")
• p(HBP:"4R tau") positiveCorrelation path(HBP:"Argyrophilic Grain Disease")
• p(HBP:"4R tau") positiveCorrelation path(MESH:"Supranuclear Palsy, Progressive")
• path(HBP:"Corticobasal Degeneration") positiveCorrelation p(HBP:"4R tau")
• path(MESH:"Niemann-Pick Diseases") positiveCorrelation p(HBP:"3R tau")
• path(MESH:"Supranuclear Palsy, Progressive") positiveCorrelation p(HBP:"4R tau")

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