path(MESH:"Alzheimer Disease") decreases p(HGNC:CHRNA3)

PubMed:19293145

However, a reduction of alpha3 subunits in a Western blot analysis of brains from patients with AD has been observed (Guan et al., 2000), although the loss was not as great as that observed for alpha4 or alpha7 subunits. In addition, alpha3 subunit levels were reduced in the temporal cortex and hippocampus of brains from patients with AD, both smokers and nonsmokers, compared with control subjects (Mousavi et al., 2003).

MeSH

Hippocampus

MeSH

Temporal Lobe

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