composite(p(HGNC:APP), p(HGNC:DKK1)) decreases a(MESH:"Dendritic Spines")

PubMed:30232325

As previously reported, Dkk1-treatment markedly reduced the number of dendritic spines on APP+/+ neurons (Fig. 3a, b). In contrast, APP-deficiency protected neurons against the synaptotoxic activity of Dkk1 (Fig. 3a, b).

Confidence

Medium

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