composite(a(HBP:"Tau aggregates"), p(HGNC:MAPT, var("p.S422E"))) increases a(HBP:"Tau oligomers")

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PubMed:27373205

Compared to monomers, aggregation significantly increased PAD exposure for both hT40 and S422E samples (Fig. 3B; F(1,12) = 685.8, p b 0.0001), as indicated by increased TNT1 reactivity. Aggregation also significantly increased oligomer formation (TOC1 reactivity) compared to monomers in both hT40 and S422E samples (Fig. 3C; F(1,12) = 109.3, p b 0.0001).

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• composite(a(HBP:"Tau aggregates"), p(HGNC:MAPT)) increases a(HBP:"Tau oligomers")

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