a(CHEBI:"alpha,alpha-trehalose") decreases a(HBP:HBP00006)

View Subject View Object

PubMed:30116051

It also proved effective in cellu- lar models of PD, HD and AD 121,122 , as well as in mouse models of HD, AD and tauopathies, where it cleared aggregates, reduced neurodegeneration and ameliorated motor and cognitive performance 123–125 .

Related Edges 6

• a(CHEBI:"alpha,alpha-trehalose") decreases bp(HP:Neurodegeneration)
• a(CHEBI:"alpha,alpha-trehalose") decreases a(HBP:HBP00016)
• a(CHEBI:"alpha,alpha-trehalose") decreases a(HBP:HBP00017)
• a(CHEBI:"alpha,alpha-trehalose") decreases a(HBP:HBP00018)
• a(CHEBI:"alpha,alpha-trehalose") increases bp(GO:"motor behavior")
• a(CHEBI:"alpha,alpha-trehalose") increases bp(GO:cognition)

MeSH

Dopaminergic Neurons

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---