a(PUBCHEM:9832404) increases a(GO:"dendritic spine")

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PubMed:30106381

The measurements showed similar patterns in both tested brain areas, with Adnp deficiency resulting in substantial decreases in spine density (male and female mice) and increases in PSD95-asymmetric shaft synapses (males only, as indicated by increased localization of PSD95 in dendritic shafts rather than spines), which were all rescued by NAP treatment.

Related Edges 3

• a(PUBCHEM:9832404) decreases p(HGNC:DLG4)
• p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) decreases a(GO:"dendritic spine")
• p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) increases p(HGNC:DLG4)

MeSH

CA1 Region, Hippocampal

MeSH

Cerebral Cortex

MeSH

Pyramidal Cells

Gender

Male

Gender

Female

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

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