bp(GO:"response to unfolded protein") increases bp(GO:"response to endoplasmic reticulum stress")

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PubMed:14556719

The UPR is a mechanism that involves a stress response in the ER, including increased biosynthesis of ER chaperones, in response to accumulation of misfolded/denatured/mutated proteins in this organelle (for a recent review on UPR, see Kaufman, 2002).

Related Edges 3

• bp(GO:"response to unfolded protein") increases a(MESH:"Molecular Chaperones")
• p(MESH:Proteins, pmod(HBP:misfolding)) increases bp(GO:"response to unfolded protein")
• p(MESH:Proteins, var("?")) increases bp(GO:"response to unfolded protein")

MeSH

Endoplasmic Reticulum

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