p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) decreases a(MESH:Neurons)

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PubMed:29202785

This may be due to the strong Tau pathology of the toxic pro-aggregant TauRDΔK leading to Tau aggregation, loss of synapses and loss of neurons

Related Edges 2

• p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) increases a(HBP:"Tau aggregates")
• p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) decreases a(GO:synapse)

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