act(p(HGNC:RIC3), ma(chap)) negativeCorrelation path(MESH:"Psychotic Disorders")

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PubMed:22040696

Interestingly, levels of RIC-3 mRNA are elevat- ed in postmortem brains of individuals with bipolar disorder and schizophrenia [181], and a link has been suggested between defi- cient RIC-3 mediated chaperoning of an AChR subunit and individ- uals with bipolar disorder and psychotic symptoms [181].

Related Edges 8

• act(p(HGNC:RIC3), ma(chap)) increases p(FPLX:CHRN)
• act(p(HGNC:RIC3), ma(chap)) negativeCorrelation path(MESH:"Bipolar Disorder")
• path(MESH:"Bipolar Disorder") positiveCorrelation r(HGNC:RIC3)
• path(MESH:"Bipolar Disorder") negativeCorrelation act(p(HGNC:RIC3), ma(chap))
• path(MESH:"Psychotic Disorders") negativeCorrelation act(p(HGNC:RIC3), ma(chap))
• path(MESH:Schizophrenia) positiveCorrelation r(HGNC:RIC3)
• r(HGNC:RIC3) positiveCorrelation path(MESH:Schizophrenia)
• r(HGNC:RIC3) positiveCorrelation path(MESH:"Bipolar Disorder")

MeSH

Brain

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