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Chaperoning α7 neuronal nicotinic acetylcholine receptors 1.0.0

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Provenance

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charles.hoyt@scai.fraunhofer.de at 2019-02-27 16:20:53.953381
Authors
Esther Wollert
Contact
charles.hoyt@scai.fraunhofer.de
License
CC BY 4.0
Copyright
Copyright © 2018 Fraunhofer Institute SCAI, All rights reserved.
Number Nodes
75
Number Edges
111
Number Components
2
Network Density
0.02
Average Degree
1.48
Number Citations
1
Number BEL Errors
0

Content Statistics

Network Overlap

The node-based overlap between this network and other networks is calculated as the Szymkiewicz-Simpson coefficient of their respective nodes. Up to the top 10 are shown below.

Network Overlap
Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection. v1.0.0 27%
albuquerque2009 v1.0.0 24%
Neuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to Nicotine v1.0.1 24%
Structural and functional properties of prefibrillar α-synuclein oligomers v1.0.0 23%
Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment v1.0.1 21%
Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous System v1.0.0 20%
Naturally-expressed nicotinic acetylcholine receptor subtypes v1.0.0 19%
NACHO Mediates Nicotinic Acetylcholine Receptor Function throughout the Brain v1.0.0 18%
Alzheimer's Disease: Targeting the Cholinergic System v1.0.0 17%
Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses v1.0.0 17%

Sample Edges

complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)) hasComponent p(HGNC:CHRNA4) View Subject | View Object

complex(p(HGNC:CHRNA4), p(HGNC:CHRNB2)) hasComponent p(HGNC:CHRNB2) View Subject | View Object

complex(a(CHEBI:"amyloid-beta"), p(HGNC:CHRNA7)) hasComponent a(CHEBI:"amyloid-beta") View Subject | View Object

complex(a(CHEBI:"amyloid-beta"), p(HGNC:CHRNA7)) hasComponent p(HGNC:CHRNA7) View Subject | View Object

complex(p(HGNC:CHRNA3), p(HGNC:CHRNB4)) hasComponent p(HGNC:CHRNA3) View Subject | View Object

Sample Nodes

a(CHEBI:"amyloid-beta")

In-Edges: 423 | Out-Edges: 245 | Children: 5 | Explore Neighborhood | Download JSON

a(HBP:HBP00018)

In-Edges: 35 | Out-Edges: 8 | Explore Neighborhood | Download JSON

bp(GO:memory)

In-Edges: 112 | Out-Edges: 33 | Explore Neighborhood | Download JSON

path(MESH:"Alzheimer Disease")

In-Edges: 536 | Out-Edges: 704 | Classes: 5 | Explore Neighborhood | Download JSON

path(MESH:Inflammation)

In-Edges: 83 | Out-Edges: 41 | Explore Neighborhood | Download JSON

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.